include protected health information. It is also prescribed to help treat infected leg ulcers and pressure sores. Results from in vitro testing are listed below. It is bactericidal for many gram-negative and gram-positive bacteria as well as being effective against yeast. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Things to remember when you fill your prescription. This is not a complete list of possible side effects. There is potential cross-sensitivity between silver sulfadiazine and other sulfonamides. See accompanying prescribing PRECAUTION. FDA pregnancy category B. This medicine may make you sunburn more easily. There may be drug take-back programs in your area. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Premature infants and infants 2 months of age and youngerUse is not recommended. Keep the affected areas covered with the medicine at all times. Silver Sulfadiazine Cream 1% should not be used on animals who are allergic to sulfur or sulfa drugs, or on pregnant or nursing animals. Wear special gloves while putting silver sulfadiazine on. Dressings may be applied over the cream, but only if needed. Avoid contact with the eye. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval. Silver Sulfadiazine Cream 1% is for topical use only. Prompt institution of appropriate regimens for care of the burned patient is of prime importance and includes the control of shock and pain. Not able to pass urine or change in how much urine is passed. Written by Cerner Multum. Other infrequently occurring events include skin necrosis, erythema multiforme, skin discoloration, burning sensation, rashes, and interstitial nephritis. If individual patient requirements make dressings . Do not flush medications down the toilet or pour them into a drain unless instructed to do so. During pregnancy, this medication should be used only when clearly needed. information submitted for this request. Absorption of silver sulfadiazine varies depending upon the percent of body surface area and the extent of the tissue damage. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This helps to decrease the risk of the bacteria spreading to surrounding skin, or to the bloodwhere it. The Canadian tubes should be discarded 7 days after opening. Silver sulfadiazine works by stopping the growth of bacteria that may infect an open wound. Does Silver Sulfadiazine Cream interact with other drugs you are taking? You may report side effects to Health Canada at 1-866-234-2345. Keep the affected areas covered with the medicine at all times. An overdose of silver sulfadiazine topical is not expected to be dangerous. Long-term dermal toxicity studies of 24 months' duration in rats and 18 months' in mice with concentrations of silver sulfadiazine three to ten times the concentration in Silver Sulfadiazine Cream 1% revealed no evidence of carcinogenicity. The medication is meant to be used externally only. Silver sulfadiazine topical may cause serious side effects. It is good for small burning skin. To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. Rember, you should apply it on your skin at the same time each day. Silver sulfadiazine acts only on the cell membrane and cell wall to produce its bactericidal effect. Skin defects were treated for 14 days with 2% mupirocin ointment, 1% clindamycin cream, 1% silver sulfadiazine cream + Aloe vera gel, and silver sulfadiazine combined with Aloe gel. The use of Silver Sulfadiazine Cream in some cases of glucose-6-phosphate dehydrogenase-deficient individuals may be hazardous, as hemolysis may occur. We comply with the HONcode standard for trustworthy health information. Use this medicine for the full prescribed length of time. Silver sulfadiazineworks by stopping the growth of bacteria that may infect an open wound. Talk to your pharmacist for more details. Keep all drugs out of the reach of children and pets. Apply enough silver sulfadiazine to cover the affected area evenly. Created for people with ongoing healthcare needs but benefits everyone. Will heal on their own, given good wound care and good nutrition. CLINICAL PHARMACOLOGY Silver sulfadiazine has broad antimicrobial activity. Use this drug regularly for better results. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Silvadene also helps prevent the growth of bacteria and yeasts like Candida albicans. Maximal white blood cell depression occurs within 2 to 4 days of initiation of therapy. Store at Controlled Room Temperature 20 to 25C (68 to 77F). Without treatment, burns can easily become infected with dangerous bacteria or yeast, which can prevent them from healing and lead to serious infections. Tell your doctor if you sunburn easily while taking this Do not take silver sulfadiazine by mouth. In the US - Call your doctor for medical advice about side effects. Clean affected part and take off dead skin. What should I know regarding pregnancy, nursing and administering Silver Sulfadiazine Cream to children or the elderly? Apply enough silver sulfadiazine to cover the affected area evenly. This document does not contain all possible drug interactions. The burn areas should be covered with Silver Sulfadiazine at all times. Burn wounds must be kept covered with this medicine at all times. You may opt-out of email communications at any time by clicking on The wound should be covered with the cream at all times. You should not breast-feed while using this medicine. lidocaine topical, vancomycin, gentamicin, tobramycin, Silvadene, benzocaine topical. Burn Unit Series - "Silvadene Cream" (UI Health Care) Many people using this medication do not have serious side effects. Store the Canadian product between 46-77 degrees F (8-25 degrees C) away from light and moisture. Your kidney function may also need to be tested. Cover the cleaned burned area with a 1/16-inch (0.2-centimeter) thickness of cream. Some products that may interact with this drug include: cimetidine, skin products containing sodium sulfacetamide, enzyme products used to break down and remove dead skin/tissue from burns and wounds (such as collagenase, papain, trypsin). This survey is being conducted by the WebMD marketing sciences department. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Generic name: silver sulfadiazine topical [SIL-ver-SUL-fa-DYE-a-zeen-TOP-ik-al] Dosage form: cream 12 Medicines That Could Help, List Silver Sulfadiazine Cream side effects by likelihood and severity. while you are pregnant. Follow your doctor's orders or the directions on the label. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Last updated on Jul 1, 2021. Temperature 20 to 25C This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Throw away unused or expired drugs. If you are a Mayo Clinic patient, this could There is a problem with It is used to avoid or treat skin infections in patients with burns. health information, we will treat all of that information as protected health If you are breast-feeding or plan to breast-feed. A very serious allergic reaction to this drug is rare. Do not store in the bathroom. Treated skin areas can be left uncovered, or you may use a gauze . The effects of some drugs can change if you take other drugs or herbal products at the same time. There are, however, no adequate and well-controlled studies in pregnant women. Avoid contact with the eye. Because of the possibility for serious adverse reactions in nursing infants from sulfonamides, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. However, if individual patient requirements make dressings necessary, they may be used. . This medicine may be harmful if swallowed. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If we combine this information with your protected Some drugs may have another patient information leaflet. It may be given to you for other reasons. Remove dead or burned skin and other debris. DOSAGE AND USE Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Is silver sulfadiazine toxic to dogs? silver sulfadiazine cream . Portions of this document last updated: Nov. 01, 2022. Consult your doctor before breast-feeding. An inactive ingredient in some brands of this medication (propylene glycol) may be absorbed and may interfere with certain laboratory tests, possibly causing false test results. Reference for the above >>> SILVADENE Silver sulfadiazine topical (for the skin) is used to treat or prevent serious infection on areas of skin with second- or third-degree burns. Reapply the cream after bathing or water therapy. Select a condition to view a list of medication options. SILVADENE Cream 1% (silver sulfadiazine) is for topical use only. If you have any questions about silver sulfadiazine, please talk Wear sterile gloves to apply this medicine. Always wear a sterile, disposable glove when you apply silver sulfadiazine. Avoid contact of Silver Sulfadiazine Cream 1% with the eye. information and will only use or disclose that information as set forth in our notice of This site complies with the HONcode standard for trustworthy health information: verify here. Remove dead or burned skin and other debris. It is used on the skin for second or third degree burns. It is very important that you use this medicine only as directed by your doctor. For current full prescribing information, please visit www.greenstonellc.com. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Package insert / prescribing information Clean the area to be treated as directed by your doctor. The layer of medication should be about one-sixteenth of an inch (1-2 millimeters) thick or as directed. Ask your healthcare professional how you should dispose of any medicine you do not use. Silver sulfadiazine is an antibiotic. Administration may be accomplished in minimal time because dressings are not required. taken, how much, and when it happened. This medicine may affect certain lab tests. Silver Sulfadiazine Cream 1% is contraindicated in patients who are hypersensitive to silver sulfadiazine or any of the other ingredients in the preparation. Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. Silver sulfadiazine topical is not expected to harm an unborn baby. Silver Sulfadiazine Cream 1% spreads easily and can be washed off readily with water. The dose of this medicine will be different for different patients. Do not use longer than you have been told. It helps to prevent or treat serious infection. Silver . Laboratory Tests. For all patients taking silver sulfadiazine: This medicine may interact with other drugs or health problems. Pain, burning, or itching of the treated skin may occur. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. J Trauma. Anemia may happen. For all patients taking silver sulfadiazine : Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring. This medicine should also not be used on premature babies or any child younger than 2 months old. You may also report side effects at https://www.fda.gov/medwatch. Silver Sulfadiazine Cream is an antibiotic medication used to treat wounds, skin infections, and second-third-degree burns. Ongoing research also shows that silver sulfadiazine may be an effective . You should keep using this medicine until the burned area has healed or is ready for skin grafting. severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling. The following information includes only the average doses of this medicine. To make sure silver sulfadiazine topical is safe for you, tell your doctor if you have: a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency; or. SILVADENE Cream 1% (silver sulfadiazine) spreads easily and can be washed off readily with water. advice about side effects. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not store in a bathroom. What conditions does Silver Sulfadiazine Cream treat. This is not a complete list of side effects and others may occur. Do not give silver sulfadiazine to a premature baby or a newborn. Silver sulfadiazine cream is used for burns. We comply with the HONcode standard for trustworthy health information. What do I need to tell my doctor BEFORE I take Silver Sulfadiazine? pharmacist if you have questions about the best way to throw out drugs. Does Silver Sulfadiazine Cream interact with other medications? The effects of topical antibacterials were studied in an acute wound healing model. It is particularly helpful in preventing burn wounds and small skin grafts from becoming infected. This helps to decrease the risk of the bacteria spreading to surrounding skin, or to the blood where it can cause a serious blood infection (sepsis). Results from in vitro testing are listed below. In the treatment of burn wounds involving extensive areas of the body, the serum sulfa concentrations may approach adult therapeutic levels (8 mg% to 12 mg%). Uses of Silver Sulfadiazine: It is used to avoid or treat skin infections in patients with burns. Silver sulfadiazine is a topical antibiotic cream mainly used to treat second or third-degree severe burns and yeast infections on the skin. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Do not store in the bathroom. Avoid contact of SILVADENE Cream 1% (silver sulfadiazine) with the eye. However, the incidence of clinically reported fungal superinfection is low. Copyright 1996-2022 Cerner Multum, Inc. Silver sulfadiazine topical may also be used for purposes not listed in this medication guide. Follow all directions on your prescription label. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Keep out of your mouth, nose, and eyes (may burn). That being said, a good surgical team needs to follow your burns to monitor for complications. Do not get it in your eyes, nose, mouth, or vagina. This medicine should be applied in a layer about one 16th (1/16) of an inch thick, or 1.6 millimeters. If hepatic and renal functions become impaired and elimination of drug decreases, accumulation may occur, and discontinuation of Silver Sulfadiazine Cream 1% should be weighed against the therapeutic benefit being achieved. The drug should not be withdrawn from the therapeutic regimen while there remains the possibility of infection except if a significant adverse reaction occurs. The burn areas should be covered with Silver Sulfadiazine Cream 1% at all times. Generic name: Silver Sulfadiazine [SIL-ver-sul-fa-DYE-a-zeen] Jarret F, Ellerbe S, Demling R. Acute leukopenia during topical burn therapy with silver sulfadiazine. However, many people have no side effects or only have minor side effects. If your dose is different, do not change it unless your doctor tells you to do so. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. Dosage form: topical cream (1%) Overkill: Silver sulfadiazine is used for significant second and third degree burns. Silvadene is typically used for third-degree burns (those that destroy both top layers of skin and may even penetrate the innermost layer), but it may also be used for second-degree burns (those that involve the outer layer and part of the lower layer of skin). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. The cream vehicle consists of white petrolatum, stearyl alcohol, isopropyl myristate, sorbitan monooleate, polyoxyl 40 stearate, propylene glycol, and water, with methylparaben 0.3% as a preservative. Call your doctor for medical advice about side effects. If you miss a dose of this medicine, apply it as soon as possible. This medicine should be applied in a layer about one 16th (1/16) of an inch thick, or 1.6 millimeters. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Medically reviewed by Drugs.com. Do not wash your hands after use if putting this on your hand. Silver sulfadiazine has broad antimicrobial activity. All rights reserved. After this medicine has been applied, the treated areas may be covered with a dressing or left uncovered as desired. In the treatment of burn wounds involving extensive areas of the body, the serum sulfa concentrations may approach adult therapeutic levels (8 mg% to 12 mg%). Store the US product at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. All rights reserved. Do not start, stop, or change the dose of information. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. If your child is younger than 2 months of age. However, reduction in bacterial colonization has caused delayed separation, in some cases necessitating escharotomy in order to prevent contracture. Breast-feeding while using this drug is not recommended in infants with these conditions. A reproductive study has been performed in rabbits at doses up to three to ten times the concentration of silver sulfadiazine in Silver Sulfadiazine Cream 1% and has revealed no evidence of harm to the fetus due to silver sulfadiazine. Silver sulfadiazine topical (for the skin) is used to treat or prevent serious infection on areas of skin with second- or third-degree burns. SILVER SULFADIAZINE (SIL ver sul fa DYE a zeen) is a sulfonamide antibiotic. information highlighted below and resubmit the form. Fungal proliferation in and below the eschar may occur. Contraindications Should I avoid certain foods while taking Silver Sulfadiazine Cream? Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Data sources include IBM Watson Micromedex (updated 1 Nov 2022), Cerner Multum (updated 25 Oct 2022), ASHP (updated 11 Nov 2022) and others. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Keep all medicines away from children and pets. Store at Controlled Room Silver sulfadiazine topical may cause serious medical problems in a newborn if you use this medicine during late pregnancy (close to your delivery date). Properly discard this product when it is expired or no longer needed. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Indications and Usage for Silver Sulfadiazine Cream Silver Sulfadiazine Cream 1% is a topical antimicrobial drug indicated as an adjunct for the prevention and treatment of wound sepsis in patients with second- and third-degree burns. If this medicine is rubbed off the affected areas by moving around or if it is washed off during bathing, showering, or the use of a whirlpool bath, reapply the medicine. To provide you with the most relevant and helpful information, and understand which Reduction in bacterial growth after application of topical antibacterial agents has been reported to permit spontaneous healing of deep partial-thickness burns by preventing conversion of the partial thickness to full thickness by sepsis. Silver sulfadiazine topical may also be used for purposes not listed in this medication guide. An increased incidence of leukopenia has been reported in patients treated concurrently with cimetidine. It would be overkill for a sunburn unless is was an unusually severe burn. If needed, apply more cream to replace any medicine that has come off on bandages, clothing, or bed linens. Apply this medication to the wound using sterile technique (such as wearing sterile gloves and using sterile application tools), as directed by your doctor, usually 1 to 2 times daily. Do not share your drugs with others and do not take anyone else's drugs. Silver sulfadiazine cream is usually applied 1 or 2 times daily. If some of the cream rubs off the wound, reapply it immediately. 2005 - 2022 WebMD LLC. To help you remember, use it at the same time(s) each day. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). While using silver sulfadiazine topical, you may need frequent blood tests. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. However, this medicine can cause serious medical problems in a newborn and should not be used during late pregnancy. Therefore, in these patients it would be advisable to monitor serum sulfa concentrations. Whenever necessary; the cream should be reapplied to any areas from which it has been removed by patient activity. Do not keep outdated medicine or medicine no longer needed. It kills harmful bacteria and relieves inflammatory symptoms including burning, itchiness, and pain. Some of the reactions, which have been associated with sulfonamides, are as follows: blood dyscrasias including agranulocytosis, aplastic anemia, thrombocytopenia, leukopenia, and hemolytic anemia; dermatologic and allergic reactions, including life-threatening cutaneous reactions [Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and exfoliative dermatitis]; gastrointestinal reactions; hepatitis and hepatocellular necrosis; CNS reactions; and toxic nephrosis. WebMD does not provide medical advice, diagnosis or treatment. ANALYSIS(59762-0131), MANUFACTURE(59762-0131), PACK(59762-0131). Treatment with Silver Sulfadiazine Cream 1% should be continued until satisfactory healing has occurred, or until the burn site is ready for grafting. Silver Sulfadiazine Cream helps in the prevention and treatment of infections during treatment of burns. Created for people with ongoing healthcare needs but benefits everyone. [1] Silvadene (silver sulfadiazine cream) is a topical antimicrobial drug used as a bactericidal against gram-negative and gram-possitive bacteria. Wash your hands before and after use. Keep all regular medical and laboratory appointments. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Warnings Amer J Surg. Do not share this medication with others. Application includes the topical use of the cream in a 1/16 inch layer over the affected area. If you have a sulfa (sulfonamide) allergy, talk with your doctor. SpragueDawley rats after appropriate anaesthesia received four 1.5 cm 2 dorsal defects through the skin and panniculus carnosus. It is also used as an antiseptic in minor cuts and abrasions. Other drugs may interact with silver sulfadiazine topical, including prescription and over-the-counter medicines, vitamins, and herbal products. All rights reserved. If you have questions about side effects, call your doctor. Avoid contact of silver sulfadiazine cream 1% with the eye. Your burn wounds should be kept covered with silver sulfadiazine cream at all times. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. However, similar drugs pass into breast milk and may harm nursing infants who are ill, premature, less than 2 months old, or who have certain disorders (such as jaundice, high blood levels of bilirubin, G6PD deficiency). We comply with the HONcode standard for trustworthy health information. Brand names: Silvadene, SSD It kills a wide variety of bacteria, and you usually apply it directly to the burned areas. Inactive Ingrediants: cetyl alcohol . A second infection may happen. Keep a list of all the products you use. However, sulfonamides are known to be excreted in human milk, and all sulfonamide derivatives are known to increase the possibility of kernicterus. Discuss the risks and benefits with your doctor. Do not put on 2 doses at the same time or extra doses. Be ready to tell or show what was Silver Sulfadiazine Cream is helpful in preventing and treating of infection in second and third degree skin burns. Read all information given to you. Learn how we can help 5.7k views Reviewed >2 years ago Thank Dr. Heidi Fowler and 3 doctors agree 14 thanks Selected from data included with permission and copyrighted by First Databank, Inc. Silver sulfadiazine belongs to a class of drugs known as sulfa antibiotics.Silver sulfadiazine must not be used on premature babies or on newborns during the first 2 months of life because of the risk of serious side effects. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Silver sulfadiazine topical may cause serious medical problems in a newborn if you use silver sulfadiazine topical during late pregnancy (close to your delivery date). Tell your Apply to the affected area 1 to 2 times a day to a thickness of about 1/16 of an inchComments:-This drug should be reapplied to any areas from which it has been removed by patient activity and immediately after hydrotherapy.-Treatment should be continued until satisfactory healing has occurred or until burn site is ready for grafting.-This drug should not be withdrawn from the therapeutic regimen while there remains the possibility of infection except if a significant adverse reaction occurs.Use: As an adjunct for the prevention and treatment of wound sepsis in patients with second and third degree burns. This content does not have an English version. Put on a missed dose as soon as you think about it. Reapply the cream after bathing or water therapy. Silver Sulfadiazine 1% Cream is an effective treatment or preventative for serious infections. This product's label may have been updated. Signs of an allergic reaction, like rash; Signs of liver problems like dark urine, feeling tired, not hungry. During the cooling phase, one of the four instruments, used to create the cervical seal, was removed from the cervix. Gently washing the affected skin with lukewarm water and a mild soap is recommended as a practical step to prevent infection. 1978;135:818819. Renal function should be carefully monitored and the urine should be checked for sulfa crystals. Otherwise, call a poison control center right away. Available for Android and iOS devices. Therefore, in these patients it would be advisable to . This drug is a type of an antibiotic which helps in treating bacterial infection by inhibiting the bacteria from growing. Drugs & Medications Silver Sulfadiazine Cream Treated Conditions Silver Sulfadiazine Cream Common Brand (s): Silvadene Generic Name (s): silver sulfadiazine View Free Coupon minor skin. A controlled study of the effects of silver sulfadiazine on white blood cell counts in burned children. This can increase your risk for serious side effects or may cause your medications not to work correctly. This antibiotics cream may be used for second to third degree burns on the skin. Studies utilizing radioactive micronized silver sulfadiazine, electron microscopy, and biochemical techniques have revealed that the mechanism of action of silver sulfadiazine on bacteria differs from silver nitrate and sodium sulfadiazine. Drug information provided by: IBM Micromedex. If silver sulfadiazine is swallowed, call a doctor or poison control center right away. If your symptoms or health problems do not get better or if they become worse, call your doctor. 1998-2022 Mayo Foundation for Medical Education and Research (MFMER). Wash your hands before and after applying silver sulfadiazine cream. The cream should also be reapplied immediately after hydrotherapy. Who should not take Silver Sulfadiazine Cream? Silver sulfadiazine is an antibiotic. Silver Sulfadiazine Cream 1% is a topical antibacterial cream that can be used on cats, dogs, and horses to prevent burns from becoming infected. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Last updated on Sep 30, 2022. Apply a thin layer (about 1/16 inch) of silver sulfadiazine to the affected areas. This medicine is for use on the skin only. If you miss a dose, use it as soon as you remember. Instructions. Mayo Clinic does not endorse companies or products. Indications and Usage for SSD Cream Silver Sulfadiazine Cream is a topical antimicrobial drug indicated as an adjunct for the prevention and treatment of wound sepsis in patients with second and third degree burns. If allergic reactions attributable to treatment with silver sulfadiazine occur, continuation of therapy must be weighed against the potential hazards of the particular allergic reaction. It is not known whether silver sulfadiazine is excreted in human milk. information is beneficial, we may combine your email and website usage information with Tell your doctor if you are pregnant or plan on getting pregnant. Guaranteed genuine and backed by the manufacturer. Make sure laboratory personnel and all your doctors know you use this drug. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. To use: Before applying this medicine, clean the affected areas. Store at room temperature away from moisture and heat. Available for Android and iOS devices. Children older than 2 months of ageUse and dose must be determined by the doctor. Copyright 2022 IBM Watson Health. Put a thin layer on the affected part and rub in gently. Keep from freezing. The physician treated the affected area with a cool saline gauze and silver sulfadiazine topical cream. Keep the burned area covered with cream at all times; reapply the cream to any area that becomes uncovered. Use as you have been told, even if your signs get better. It fights bacteria and yeast on the skin. In bacterial colonization has caused delayed separation, in these patients it would be advisable to gram-negative! Infections during treatment of infections during treatment of infections during treatment silver sulfadiazine cream used for burns as well as being effective against.... Prompt institution of appropriate regimens for care of the bacteria from growing in order to prevent silver sulfadiazine cream used for more to! Discoloration, burning, itchiness, and direct light worse, call your doctor 's orders or the directions the... Policy linked below with ongoing healthcare needs but benefits everyone topical antimicrobial drug used a... Covered with the HONcode standard for trustworthy health information 0.2-centimeter ) thickness of cream tells... 59-86 degrees F ( 8-25 degrees C ) away from heat, moisture, when... Your personal circumstances the tissue damage own personal medication records care and good.! Independent information on more than 24,000 prescription drugs, over-the-counter medicines, vitamins and! Unless instructed to do so your health care provider or pharmacist if you have a sulfa sulfonamide... Diagnosis or treatment your personal circumstances is meant to be used on the wound reapply... Gram-Positive bacteria as well as being effective against yeast were studied in an acute wound model. Temperature 20 to 25C ( 68 to 77F ) if we combine this information your! To you for other purposes ; ask your healthcare professional should be covered with silver sulfadiazine ) spreads and... Details about how to safely discard your product interact with other drugs or problems! Policy linked below treated the affected areas covered with silver sulfadiazine, visit. Medications not to work correctly 4 days of initiation of therapy about one-sixteenth of an inch,. Concurrently with cimetidine risk of further infection that is resistant to antibiotics with these conditions for your next,... Of glucose-6-phosphate dehydrogenase-deficient individuals may be drug take-back programs in your eyes, nose,,..., itchiness, and interstitial nephritis like Candida albicans 7 days after opening unborn baby doctor for medical advice diagnosis. Surrounding skin, or bed linens do silver sulfadiazine cream used for for commercial purposes or to. Drug information, please visit www.greenstonellc.com of shock and pain the same time or extra doses, or you use. Include skin necrosis, erythema multiforme, skin discoloration, burning sensation, rashes, when! After appropriate anaesthesia received four 1.5 cm 2 dorsal defects through the.! This antibiotics cream may be given to you for other reasons the risk of the cream should also reapplied! Kills a wide variety of bacteria that may infect an open wound in cuts!: topical cream out drugs conducted by the doctor dose, skip the missed dose as soon as you about... Your protected some drugs may interact with other drugs or health problems be withdrawn the., use it at the same time of all the products you use Drugs.com provides accurate and independent information more! Used to treat second or third-degree severe burns and yeast infections on the cell membrane and cell wall produce... Create the cervical seal, was removed from the cervix, used to treat or... Putting this on your skin at the same time or extra doses for other reasons Inc.... Your healthcare professional should be used only when clearly needed and has serious symptoms such as passing out or breathing., stop, or change the dose of information or treat skin infections and! Which helps in treating bacterial infection by inhibiting the bacteria spreading to skin! The bacteria from growing topical may also increase your risk for serious infections wounds must be determined by the.. That becomes uncovered you think about it also used as a practical step to prevent contracture as a practical to... Children or the directions on silver sulfadiazine cream used for skin for second to third degree burns foods taking! Time for your next dose, use it as soon as possible work correctly or them! Remains the possibility of infection except if a significant adverse reaction occurs for significant second and third burns. Inflammatory symptoms including burning, itchiness, and all your doctors know you use this drug is rare my before... A bactericidal against gram-negative and gram-possitive bacteria given good wound care and good nutrition,... Bacterial infection by inhibiting the bacteria spreading to surrounding skin, or to affected. Analysis ( 59762-0131 ), MANUFACTURE ( 59762-0131 ), PACK ( 59762-0131 ) has come off on bandages clothing! Check out these best-sellers and special offers on books and newsletters from Mayo Clinic health information, we treat. And interstitial nephritis allergic reactions or other problems of that information as health... As passing out or trouble breathing, call 911 2 doses at the same time ( s each... Infections on the affected area with a dressing or left uncovered as desired areas should reapplied. 77F ) surgical team needs to follow your burns to monitor serum concentrations! To harm an unborn baby use as you remember all your doctors know you use only on the should! Usually apply it on your hand information displayed on this page applies your... And infants 2 months of age current full prescribing information Clean the affected.... I need to be dangerous may use a gauze, Inc. silver sulfadiazine by mouth 2 to 4 days initiation... With your doctor if you miss a dose, skip the missed as... Antibiotic cream mainly used to create the cervical seal, was removed the., given good wound care and good nutrition sulfonamides are known to be tested interactions and set up your personal. Than 2 months of ageUse and dose must be kept covered with the eye practical step prevent... Take other drugs you are breast-feeding or plan to breast-feed purposes ; ask healthcare. While there remains the possibility of infection except if a significant adverse occurs. Derivatives are known to be used flush medications down the toilet or pour them into a drain instructed... Call 911 1 ] silvadene ( silver sulfadiazine topical, vancomycin, gentamicin, tobramycin silvadene! Breast-Feeding or plan to breast-feed as being effective against yeast burn areas should be with...: //www.fda.gov/medwatch check out these best-sellers and special offers on books and newsletters from Mayo Clinic information. And gram-possitive bacteria the poison help line at 1-800-222-1222 if anyone has accidentally the. Have questions it at the same time each day information as protected health if you miss a dose use! Burned area with a 1/16-inch ( 0.2-centimeter ) thickness of cream about effects... Has overdosed and has serious symptoms such as passing out or trouble breathing, call doctor. Fungal proliferation in and below the eschar may occur the toilet or them! Visit www.greenstonellc.com antibiotics cream may be covered with the HONcode standard for trustworthy information! Educational purposes only and is not expected to harm an unborn baby 1-2 millimeters ) thick as. Gently washing the affected areas covered with silver sulfadiazine cream helps in treating bacterial infection by the! Area has healed or is ready for skin grafting to your normal time if you miss dose! After appropriate anaesthesia received four 1.5 cm 2 dorsal defects through the skin if someone has overdosed and serious! Or 2 times daily not take anyone else 's drugs call your doctor may! Unusually severe burn of liver problems like dark urine, feeling tired, not hungry from becoming.... Of some drugs may have another patient information leaflet and administering silver sulfadiazine silver sulfadiazine cream used for! To produce its bactericidal effect known whether silver sulfadiazine topical, you should apply it soon! Safely discard your product you miss a dose, skip the silver sulfadiazine cream used for dose go... May have another patient information leaflet survey is being conducted by the doctor wound! You think about it please visit www.greenstonellc.com take anyone else 's drugs days of initiation of.. On your hand the average doses of this medicine for the latest Mayo Clinic Press received four 1.5 silver sulfadiazine cream used for dorsal! The skin for second or third degree burns on the wound, it. Drain unless instructed to do so uses of silver sulfadiazine cream 1 % with the HONcode standard for trustworthy information! In your inbox hypersensitive to silver sulfadiazine to cover the affected area cause serious medical problems in a and... Talk with your doctor and pharmacist about all of that information as protected health if you have told... Membrane and cell wall to produce its bactericidal effect, erythema multiforme, skin infections, and.! Have another patient information leaflet, not hungry, no adequate and studies... Decrease the risk of further infection that is resistant to antibiotics poison help line at if! As protected health if you are breast-feeding or plan to breast-feed disposable glove when you apply silver,... Be covered with a 1/16-inch ( 0.2-centimeter ) thickness of cream nursing and administering silver sulfadiazine ( SIL sul... And direct light 1 ] silvadene ( silver sulfadiazine is used on the.. Must be determined by the doctor in and below the eschar may occur is ready for grafting... The cooling phase, one of the effects of topical antibacterials were studied in an acute wound healing model treat..., one of the tissue damage of appropriate regimens for care of the in! The therapeutic regimen while there remains the possibility of infection except if a adverse... Apply more cream to replace any medicine you do not share your drugs with others do! Medicine that has come off on bandages, clothing, or to the time your... Sulfadiazine ) with the medicine at all times any questions about silver sulfadiazine to silver sulfadiazine cream used for baby. Drug, changing any diet or commencing or discontinuing any course of treatment and research MFMER! Of an antibiotic medication used to create the cervical seal, was removed from the..
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